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Parameter
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Per protocol group (N= 82)
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ITT group (N= 97)a
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Missed patientsb(N= 80)
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|---|
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Age (median, IQR)
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47 (40 to 55)
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48 (40 to 55)
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49 (41 to 56)
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Gender (N, %)
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43, 52%
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53, 55%
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36, 46%
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Arrival by ambulance (N, %)
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59, 72%
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70, 72%
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62, 79%
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Killip class 1 (N, %)
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81, 99%
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95, 98%
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76, 96%
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History of hypertension (N, %)
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17, 21%
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20, 21%
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16, 20%
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History of diabetes (N, %)
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5, 6%
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5, 5%
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2, 3%
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History of elevated cholesterol/cholesterol treatment (N, %)
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16, 20%
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18, 19%
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21, 27%
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Smoker (N, %)
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27, 33%
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32, 33%
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16, 20%
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Family history CAD (N, %)
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22, 27%
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28, 29%
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22, 28%
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Hospital admission (N, %)
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3, 4%
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5, 5%
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6, 8%
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GRACE risk score (median, IQR)
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70 (60 to 88)
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70 (59 to 88)
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77 (60 to 89)
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GRACE freedom from events score (median, IQR)
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323 (312 to 333)
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323 (311 to 333)
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325 (312 to 336)
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MACE at 7 days (N, %, 95% CI)
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0, 0%, 0% to 4.5%
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0, 0%, 0% to 3.8%
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0, 0%, 0% to 4.6%
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MACE at 30 days (N, %, 95% CI)
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0, 0%, 0% to 4.5%
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0, 0%, 0% to 3.8%
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0, 0%, 0% to 4.6%
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MACE or revascularization at 30 days (N, %, 95% CI)
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0, 0%, 0% to 4.5%
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0, 0%, 0% to 3.8%
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1, 1.3%, 0.2% to 6.8%
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- ITT, intention to treat; IQR, interquartile range; CAD, coronary artery disease; GRACE, Global Risk Acute Coronary Events Registry; MACE, major adverse cardiac events. aIncludes per protocol group; bstandard biomarker interval only, no 2-h specimen.